Apheresis in Adult With Refractory Idiopathic Nephrotic Syndrome on Native Kidneys
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Apheresis in Adult With Refractory Idiopathic Nephrotic Syndrome on Native Kidneys |
| Type de publication | Journal Article |
| Year of Publication | 2021 |
| Auteurs | Moret L, Ganea A, Dao M, Hummel A, Knebelman B, Subra JFrancois, Noble J, Mariat C, Jourde-Chiche N, Toure F, Garrouste C, Laurent C, Adeline L, Delmas Y, Cez A, Fritz O, Mousson C, Pouteau LMarie, Moranne O, Halimi J-M, Audard V |
| Journal | KIDNEY INTERNATIONAL REPORTS |
| Volume | 6 |
| Pagination | 2134-2143 |
| Date Published | AUG |
| Type of Article | Article |
| ISSN | 2468-0249 |
| Mots-clés | apheresis, focal segmental glomerulosclerosis, minimal change nephrotic syndrome, nephrotic syndrome |
| Résumé | {Background: Apheresis is the gold standard for idiopathic nephrotic syndrome (INS) relapse after transplantation, but it remains unknown whether such treatment is useful for adults with refractory INS on native kidneys. Methods: This retrospective study included patients older than 16 years with biopsy-proven refractory (persistent nephrotic syndrome on corticosteroids plus at least 1 immunosuppressive drug) INS treated by apheresis and followed for at least 3 months. Results: Between September 1997 and January 2020, 21 patients (focal segmental glomerulosclerosis: 12, minimal change nephrotic syndrome: 9, men: 67%, median age: 34 years) were identified. At last follow-up (12 months), 7 of 21 patients were in complete or partial remission. Remission was associated with older age (51 vs. 30 years |
| DOI | 10.1016/j.ekir.2021.04.029 |