Usefulness and limitations of contractile reserve evaluation in patients with low-flow, low-gradient aortic stenosis eligible for cardiac resynchronization therapy
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Usefulness and limitations of contractile reserve evaluation in patients with low-flow, low-gradient aortic stenosis eligible for cardiac resynchronization therapy |
| Type de publication | Journal Article |
| Year of Publication | 2014 |
| Auteurs | Garnier F, Eicher J-C, Jazayeri S, Bertaux G, Bouchot O, Aho L-S, Wolf J-E, Laurent G |
| Journal | EUROPEAN JOURNAL OF HEART FAILURE |
| Volume | 16 |
| Pagination | 648-654 |
| Date Published | JUN |
| Type of Article | Article |
| ISSN | 1388-9842 |
| Mots-clés | Aortic valve stenosis, Cardiac resynchronization therapy, Dobutamine stress echocardiography, Left bundle branch block, Ventricular dysfunction |
| Résumé | {AimsIn low-flow, low-gradient aortic stenosis (LF/LG AS), the assessment of contractile reserve (CR) by dobutamine stress echocardiography (DSE) is recommended for risk stratification and treatment strategy. However, DSE may show limitations in cases of left ventricular dyssynchrony (LVD). The impact of LVD in LF/LG AS, and the feasibility of CRT in this setting have never been evaluated. We aimed to assess: (i) the proportion of LF/LG AS patients with LVD; (ii) the influence of LVD on CR at DSE; and (iii) the effects of CRT in these patients. Methods and resultsThirty consecutive patients with LF/LG AS underwent DSE with study of CR. The operative risk for aortic valve replacement (AVR) was assessed using the logistic EuroSCORE. Twenty-one of the 30 patients had LVD. They were significantly older, more symptomatic, had a higher EuroSCORE, and a lower prevalence of CR than those with a narrow QRS (47% vs. 100% |
| DOI | 10.1002/ejhf.78 |