Triterpenoid saponins from Polycarpaea corymbosa Lamk. var. eriantha Hochst
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | Triterpenoid saponins from Polycarpaea corymbosa Lamk. var. eriantha Hochst |
| Type de publication | Journal Article |
| Year of Publication | 2014 |
| Auteurs | Manase MJaovita, Mitaine-Offer A-C, Miyamoto T, Tanaka C, Delemasure S, Dutartre P, Lacaille-Dubois M-A |
| Journal | PHYTOCHEMISTRY |
| Volume | 100 |
| Pagination | 150-155 |
| Date Published | APR |
| Type of Article | Article |
| ISSN | 0031-9422 |
| Mots-clés | Caryophyllaceae, Cytotoxicity, NMR, Polycarpaea corymbosa, Triterpene saponins |
| Résumé | Four triterpenoid saponins (1-4) were isolated from Polycarpaea corymbosa Lamk. var. eriantha Hochst along with the known apoanagallosaponin IV (5). Their structures were elucidated by spectroscopic data analysis. Among the compounds 1, 3-5 which were evaluated for their cytotoxicity against three tumor cell lines (SW480, DU145 and EMT6), compound 1 exhibited cytotoxicity with IC50 values ranging from 4.61 to 22.61 mu M, which was greater than that of etoposide. Compound 2 was tested only against SW480 and a cardiomyoblast cell line (H9c2), and was inactive. (C) 2013 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.phytochem.2013.12.005 |