Vascular Aphasia Outcome after Intravenous Recombinant Tissue Plasminogen Activator Thrombolysis for Ischemic Stroke

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TitreVascular Aphasia Outcome after Intravenous Recombinant Tissue Plasminogen Activator Thrombolysis for Ischemic Stroke
Type de publicationJournal Article
Year of Publication2014
AuteursJacquin A., Virat-Brassaud M.-E, Rouaud O., Osseby G.-V, Aboa-Eboule C., Hervieu M., Menassa M., Ricolfi F., Giroud M., Bejot Y.
JournalEUROPEAN NEUROLOGY
Volume71
Pagination288-295
Type of ArticleArticle
ISSN0014-3022
Mots-clésConduction aphasia, Stroke, thrombolysis
Résumé

{Introduction: No data about the specific outcome of aphasia after thrombolysis are available. Our aim was to describe the severity and type of aphasia after stroke thrombolysis. Methods: This retrospective cohort study included consecutive aphasic patients hospitalized in the Stroke Unit of Dijon (University Hospital, France) between 2004 and 2009 for a firstever ischemic stroke of the left middle cerebral artery. Aphasic syndromes and their severity (French version of the Boston Diagnostic Aphasia Examination) were evaluated during the first week and 3 months after stroke. Results: In multivariate analyses, the severity of aphasia in the 37 thrombolysed patients was milder than in the 38 nonthrombolysed patients during the first week (adjusted OR = 10.13, 95% CI: 2.43-42.28

DOI10.1159/000357428