Relevance of impedance spectroscopy for the monitoring of implant-induced fibrosis: a preliminary study

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TitreRelevance of impedance spectroscopy for the monitoring of implant-induced fibrosis: a preliminary study
Type de publicationConference Paper
Year of Publication2015
AuteursLewis N., Lahuec C., Renaud S., McAdams E., Bogonez-Franco P., Lethias C., Kellouche S., Carreiras F., Pinna A., Histace A., Boissiere M., Pauthe E., Lagroye I., Soulier F., Bernard S., Binczak S., Granado B., Garda P., Terosiet M., Goguin A., Romain O.
Conference Name2015 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (BIOCAS)
PublisherIEEE; IEEE Circuits & Syst Soc; IEEE Engn Med & Biol Soc; IEEE Solid State Circuits Soc; Natl Sci Fdn; Medtron Inc; St Jude Med
Conference Location345 E 47TH ST, NEW YORK, NY 10017 USA
ISBN Number978-1-4799-7234-0
Mots-clésElectronic Implant, Embedded System, fibrosis, Impedance spectroscopy, Medical Devices
Résumé

This paper focuses on the study of fibrosis induced by an implanted medical device and explores the possibility of characterizing this process by in situ measurement of electrical impedance. The approach combines concurrent electrical and biological characterizations of fibrotic tissue, applied to electrodes implanted in an animal model. The methodology used is described. Initial results evidence the strong correlation between fibrotic tissue and electrical parameters. Identification of such electrical parameters will enable the establishment of a reliable monitoring method.