A General Palladium-Catalyzed Method for Alkylation of Heteroarenes Using Secondary and Tertiary Alkyl Halides
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | A General Palladium-Catalyzed Method for Alkylation of Heteroarenes Using Secondary and Tertiary Alkyl Halides |
| Type de publication | Journal Article |
| Year of Publication | 2014 |
| Auteurs | Wu X, See JWei Ting, Xu K, Hirao H, Roger J, Hierso J-C, Zhou J(Steve) |
| Journal | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION |
| Volume | 53 |
| Pagination | 13573-13577 |
| Date Published | DEC 1 |
| Type of Article | Article |
| ISSN | 1433-7851 |
| Mots-clés | alkyl radicals, C-H activation, heterocycles, Palladium, single electron transfer |
| Résumé | A general alkylation of heterocycles using a simple palladium catalyst is reported. Most classes of heterocycles, including indoles and pyridines, efficiently coupled with unactivated secondary and tertiary alkyl halides. An alkyl radical addition to neutral heteroarenes is most likely involved. |
| DOI | 10.1002/anie.201408355 |