Genome-wide Association Study Identifies Five Susceptibility Loci for Follicular Lymphoma outside the HLA Region

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TitreGenome-wide Association Study Identifies Five Susceptibility Loci for Follicular Lymphoma outside the HLA Region
Type de publicationJournal Article
Year of Publication2014
AuteursSkibola CF, Berndt SI, Vijai J, Conde L, Wang Z, Yeager M, de Bakker PIW, Birmann BM, Vajdic CM, Foo J-N et al.
JournalAMERICAN JOURNAL OF HUMAN GENETICS
Volume95
Pagination462-471
Date PublishedOCT 2
Type of ArticleArticle
ISSN0002-9297
Résumé

{Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously identified human leukocyte antigen (HLA) gene variants. To identify additional FL susceptibility loci, we conducted a large-scale two-stage GWAS in 4,523 case subjects and 13,344 control subjects of European ancestry. Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573
DOI10.1016/j.ajhg.2014.09.004