Red/NIR neutral BODIPY-based fluorescent probes for lighting up mitochondria
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Titre | Red/NIR neutral BODIPY-based fluorescent probes for lighting up mitochondria |
Type de publication | Journal Article |
Year of Publication | 2021 |
Auteurs | Yang J, Zhang R, Zhao Y, Tian J, Wang S, Gros CP, Xu H |
Journal | SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY |
Volume | 248 |
Pagination | 119199 |
Date Published | MAR 5 |
Type of Article | Article |
ISSN | 1386-1425 |
Mots-clés | BODIPY, fluorescent probes, Imaging, Mitochondria |
Résumé | Two mitochondrial-targeted fluorescent probes, 2 and 3, based on a BODIPY scaffold and one or two piperidinyl groups were easily synthesized by Knoevenagel condensation. The biological imaging applications of the two probes 2 and 3 in live HepG2 cells reveal that these two probes display excellent mitochondrial imaging ability. Thus, these probes appear as promising tools for visualization of mitochondrial within live cells. (C) 2020 Elsevier B.V. All rights reserved. |
DOI | 10.1016/j.saa.2020.119199 |