Red/NIR neutral BODIPY-based fluorescent probes for lighting up mitochondria

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TitreRed/NIR neutral BODIPY-based fluorescent probes for lighting up mitochondria
Type de publicationJournal Article
Year of Publication2021
AuteursYang J, Zhang R, Zhao Y, Tian J, Wang S, Gros CP, Xu H
JournalSPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
Volume248
Pagination119199
Date PublishedMAR 5
Type of ArticleArticle
ISSN1386-1425
Mots-clésBODIPY, fluorescent probes, Imaging, Mitochondria
Résumé

Two mitochondrial-targeted fluorescent probes, 2 and 3, based on a BODIPY scaffold and one or two piperidinyl groups were easily synthesized by Knoevenagel condensation. The biological imaging applications of the two probes 2 and 3 in live HepG2 cells reveal that these two probes display excellent mitochondrial imaging ability. Thus, these probes appear as promising tools for visualization of mitochondrial within live cells. (C) 2020 Elsevier B.V. All rights reserved.

DOI10.1016/j.saa.2020.119199