Blastic Plasmacytoid Dendritic Cell Neoplasm Clinical Presentation and Diagnosis
| Affiliation auteurs | Affiliation ok |
| Titre | Blastic Plasmacytoid Dendritic Cell Neoplasm Clinical Presentation and Diagnosis |
| Type de publication | Journal Article |
| Year of Publication | 2020 |
| Auteurs | Deconinck E, Petrella T, Ottou FGarnache |
| Journal | HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA |
| Volume | 34 |
| Pagination | 491-500 |
| Date Published | JUN |
| Type of Article | Article |
| ISSN | 0889-8588 |
| Mots-clés | Anatomopathology, BPDCN, Clinical presentation, Diagnosis, Immunophenotyping, Morphologies |
| Résumé | Clinical and biological presentation of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) is depicted to highlight criteria that might alert physicians. Diagnosis of BPDCN is still challenging and requires (1) immunophenotyping of blood or bone marrow aspiration using several markers (CD4, CD56, HLA-DR, myeloid and lymphoid lineage markers) and should include pDC markers such as CD123, cTCL1, CD303, and CD304, and/or (2) pathologic analysis of cutaneous lesions, also with immunohistochemistry using markers specific to BPDCN. |
| DOI | 10.1016/j.hoc.2020.01.010 |