Study and optimization of freeze-drying cycles of a model probiotic strain

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TitreStudy and optimization of freeze-drying cycles of a model probiotic strain
Type de publicationConference Paper
Year of Publication2018
AuteursVerlhac P., Vessot-Crastes S., Degobert G., Cogne C., Andrieu J., Beney L., Gervais P.
EditorCarcel JA, Clemente G, GarciaPerez JV, Mulet A, Rossello C
Conference NameIDS'2018: 21ST INTERNATIONAL DRYING SYMPOSIUM
PublisherUniv Politecnica Valencia; Generalitat Valenciana, Conselleria Educac Investigac Cultura Deporte; Univ Illes Balears; FRESENIUS KABI; Glatt; Univ Politecnica Valencia, Catedrainia; Assoc Francaise Sechage Ind Agr; Biopartner Labs; BORRELL
Conference LocationCAMINO VERA S-N, VALENCIA, 46022, SPAIN
ISBN Number978-84-9048-688-7
Mots-clésFreeze-drying, Freezing, L. Casei ATCC 393, Probiotics
Résumé

This work is based on the experimental study of the freeze-drying process to understand the impact of numerous factors on the survival rates of a model probiotic strain of Lactobacillus casei type. With the aim to find out if cell density in the matrix and survival rates are linked, we have studied the location of the cells after freeze drying inside a porous matrix composed of a lactose basis with a polymer, the polyvinylpyrrolidone (PVP) in various amounts. The best survival rate were obtained at slow freezing rate for a formulation containing 5% (m/V) of lactose and 5% (m/V) of PVP.

DOI10.4995/ids2018.2018.7400