FDG Brain PET/CT Revealing Bilateral Thalamostriatal Activation During a Symptomatic Episode in a Patient With Kleine-Levin Syndrome

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TitreFDG Brain PET/CT Revealing Bilateral Thalamostriatal Activation During a Symptomatic Episode in a Patient With Kleine-Levin Syndrome
Type de publicationJournal Article
Year of Publication2017
AuteursDrouet C, Morel O, Verger A, Guedj E, Boulahdour H
JournalCLINICAL NUCLEAR MEDICINE
Volume42
PaginationE261-E262
Date PublishedMAY
Type of ArticleEditorial Material
ISSN0363-9762
Mots-clésFDG, Kleine-Levin syndrome, PET, striatum, thalamus
Résumé

We report the case of a 14-year-old girl with clinically diagnosed Kleine-Levin syndrome. Electroencephalogram and brain MRI were unremarkable. An FDG PET/CT scan was acquired during a symptomatic episode, while she was asleep, and another PET scan was obtained when she was asymptomatic, awake, and quiet. Comparison of both examinations demonstrated a bilateral activation of thalami, caudate nuclei, and lenticular nuclei. These findings may be linked to the implication of thalamostriatal structures in the regulation of sleep and wakefulness.

DOI10.1097/RLU.0000000000001616