``Pro-youthful'' factors in the ``labyrinth'' of cardiac rejuvenation
| Affiliation auteurs | !!!! Error affiliation !!!! |
| Titre | ``Pro-youthful'' factors in the ``labyrinth'' of cardiac rejuvenation |
| Type de publication | Journal Article |
| Year of Publication | 2016 |
| Auteurs | Rochette L, Vergely C |
| Journal | EXPERIMENTAL GERONTOLOGY |
| Volume | 83 |
| Pagination | 1-5 |
| Date Published | OCT |
| Type of Article | Review |
| ISSN | 0531-5565 |
| Mots-clés | Cardiac, FSTL1, GDF11, IGF-I, Rejuvenation |
| Résumé | The mechanisms of aging and senescence include various endogenous and exogenous factors. Among cardiovascular diseases, heart failure is a typical age-related disease. New strategies to restore cardiomyocyte cells have been reported: endogenous substances that can regenerate the heart's cardiomyocytes have been described: follistatin like 1 (FSTL1), growth-differentiation factor 11 (GDF11) and insulin-like growth factor 1 (IGF-I). Manipulation of the different anti and pro-pathways is essential to discover new approaches to regenerative therapies. (C) 2016 Elsevier Inc. All rights reserved. |
| DOI | 10.1016/j.exger.2016.07.004 |